Web:A. aegypti Homepage

From VectorBase Help System

Jump to: navigation, search

question_32.png A. aegypti Homepage
Go to the A. aegypti home page.

Contents

[edit] Aedes aegypti

Aedes aegypti, commonly known as the yellow fever mosquito, is a mosquito that can host the dengue fever, Chikungunya and yellow fever viruses.

[edit] Source of the Liverpool strain used in sequencing

The Aedes aegypti Liverpool (LVP) strain sequenced for this genome project originated from West Africa and was maintained at the Liverpool School of Tropical Medicine starting in 1936. It was selected for susceptibility to the filarial worm parasite Brugia malayi [1], and then subsequently a substrain (LVP^sbm) was selected for greater Brugia susceptibility [2][3]. Genome sequencing was performed on DNA purified from newly hatched larvae of an LVP^sbm strain which was derived after 12 consecutive generations of single pair inbreeding. This inbred strain has been designated Aedes aegypti LVP^1b12.

[edit] Genome

The A. aegypti genome is approximately 1.38 Gb in size with a GC content of 38.2%. Aedes has 3 chromosomes (designated chromosomes 1, 2 and 3). Data related to the genome project have been deposited in GenBank under the project accession: AAGE02000000.

A genome analysis paper was published in June 2007[4].

[edit] References

  1. ↑ Macdonald, WW. (1963) Further studies on a strain of Aedes aegypti susceptible to infection with sub-periodic Brugia malayi. Ann. Trop. Med. Parasitol. 57:452-60. PMID: 14101936
  2. ↑ Beernsten, BT, et al. (1995) Aedes aegypti: a quantitative trait locus (QTL) influencing filarial worm intensity is linked to QTL for susceptibility to other mosquito-borne pathogens. Exp. Parasitol. 81(3):355-62 PMID: 7498432
  3. ↑ Severson, DW, et al. (1995) Restriction fragment length polymorphism mapping of quantitative trait loci for malaria parasite susceptibility in the mosquito Aedes aegypti. Genetics 139(4):1711-7. PMID: 7789771
  4. ↑ Nene, V, et al. (2007) Genome sequence of Aedes aegypti, a major arbovirus vector. Science, 316 (5832), 1718-23. PMID: 17510324


[edit] Links to VectorBase site


Relevant pages within VectorBase
HomePage » Genome
Retrieved from "http://www.vectorbase.org/Help/Web:A._aegypti_Homepage"
Personal tools